MCDB










Biological Sensing and the Dynamics of Behavior

Thierry Emonet

Assistant Professor of Molecular, Cellular and Developmental Biology
Room: KBT 1048
Phone: 203-432-3516
Email: thierry.emonet@yale.edu
Lab: http://emonet.biology.yale.edu

Dipl. Phys. ETHZürich (M.S.) , 1992; Ph.D., University of La Laguna, Spain, 1998

We are interested in biological sensing and decision making. We study how bacteria sense and explore their environment, how flies smell, and how T cells decide to mount or not an immune response. We use experiments and mathematical modeling to study the dynamical properties of biological systems and uncover the molecular origin of behavior. Our lab employs a mixture of biologists, physicists, computer scientists and mathematicians. For more information please visit our website.

Selected Publications

Sneddon, M.W., Faeder, J.R., Emonet, T., Efficient Modeling, Simulation and Coarse-graining of Biological Complexity with NFsim, under review

Llopis PM, Jackson AF, Sliusarenko O, Surovtsev I, Heinritz J, Emonet T, Jacobs-Wagner C, Spatial organization of the flow of genetic information in bacteria, Nature, 466(7302):77-81 (2010).

Sliusarenko O, Cabeen M, Wolgemuth C, Jacobs-Wagner C, Emonet T., The processivity of peptidoglycan synthesis provides a built-in mechanism for the robustness of straight-rod cell morphology, Proc. Natl. Acad. Sci., 107(22):10086-91 (2010).

Alexander RP, Kim PM, Emonet T, and Gerstein MB, Understanding Modularity in Molecular Networks Requires Dynamics, Sci. Signal., 81(2):44 (2009).

Alyahya SA, Alexander R, Costa T, Henriques AO, Emonet T, and Jacobs-Wagner C., RodZ, a component of the bacterial core morphogenic apparatus, Proc. Natl. Acad. Sci., 106(4):1239-44 (2009).

Emonet T, Cluzel P, Relationship between cellular response and behavioral variability in bacterial chemotaxis, Proc. Natl. Acad. Sci., 105(9):3304-9(2008).

Korobkova E*, Emonet T*, Vilar JM, Shimizu TS, Cluzel P. (2004) From molecular noise to behavioural variability in a single bacterium. Nature 428:574-8. *Contributed equally.

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